Journal of Critical and Intensive Care
2021 , Vol 12, Issue 2
Transfusion-Related Acute Lung Injury (TRALI) After Convalescent Plasma Therapy in COVID-19 Patient
1Van Yuzuncu Yıl University Faculty of Medicine Department of Chest Diseases, Van, Turkey
DOI :
10.37678/dcybd.2021.2683
The coronavirus disease 2019 (COVID-19) continues to spread all around the world. Mortality and morbidity
rates are increasing-up to now. Although convalescent plasma therapy can be thought to be useful in the
treatment of COVID-19, it carries potential risks, such as transfusion-related acute lung injury (TRALI). In
COVID-19 infection, tachypnea, tachycardia, increased need for oxygenation, and the presence of bilateral
widespread infiltrates on radiological imagings are evaluated as acute respiratory distress syndrome (ARDS).
This clinical situation may develop independently from disease progression in patients receiving convalescent
plasma therapy and it is called TRALI. We aimed to present our case to discuss the difficulty of this situation
to differentiate from COVID-19 related ARDS.
Keywords :
COVID-19, Convalescent Plasma, Transfusion-Related Acute Lung Injury, Acute Respiratory Distress Syndrome