Journal of Medical and Surgical Intensive Care Medicine 0 , Vol 0, Issue 0
An Adverse Event Associated with Antifungal Therapy: Clinic-Like Posterior Reversible Encephalopathy Syndrome
Ayşın Kısabay Ak 1 , Melike Batum 1 , Hatice Mavioğlu 1 , Serpil Erbüyün 2 , Deniz Heppekcan 3 , Demet Aydın Tok 3 , Recep Boyacı 4
1Manisa Celal Bayar Üniversitesi Tıp Fakültesi, Hafsa Sultan Hastanesi, Nöroloji Anabilim Dalı, Manisa, Türkiye
2Manisa Devlet Hastanesi, Anesteziyoloji ve Reanimasyon Kliniği, Manisa , Türkiye
3Manisa Celal Bayar Üniversitesi Tıp Fakültesi, Hafsa Sultan Hastanesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Manisa, Türkiye
4Bozüyük Devlet Hastanesi, Nöroloji Kliniği, Bilecik, Türkiye
DOI : 10.5152/dcbybd.2018.1700

Posterior reversible encephalopathy syndrome (PRES) is a diagnosis characterized by headache, changes in consciousness, epileptic seizures, visual symptoms (decreased visual acuity and blurred vision), vasospasm, and perfusion abnormalities in the posterior systemic vessels of the brain. The most common clinical findings of PRES include headache, epileptic seizure, altered consciousness, motor deficits, and loss of vision. In the patient who presented with symptoms similar to those in PRES after the use of anidulafungin and had a history of trauma, other causes of PRES (like carotid and/or vertebral artery dissection, intra-abdominal trauma, and head trauma etc.) were excluded. In our case, visual disturbance was assessed as being secondary to central nervous system pathology. There are no similar cases in the literature that presented with clinical features of PRES and normal imaging findings. The primary aim of this study was to draw attention to the fact that anidulafungin may cause symptoms similar to those in PRES.


Cite this article as
: Kısabay Ak A, Erbüyün S, Heppekcan D, et al. An Adverse Event Associated with Antifungal Therapy: Clinic-Like Posterior reversible ensefalopati sendromu (PRES). Yoğun Bakım Derg 2018; 10.5152/dcbybd.2018.1700

Keywords : Posterior reversible encephalopathy syndrome headache, epileptic seizure, cortical blindness, side effect